Ronaldo Aloise Pilli*, Ian de Toledo, Matheus Andrade Meirelles and Thiago Augusto Grigolo Pages 7372 - 7451 ( 80 )
This review covers the chemistry and biological aspects of goniothalamin-related styryl lactones isolated from natural sources. This family of secondary metabolites has been reported to display diverse uses in folk medicine, but only a limited number of these compounds have been throughly investigated regarding their biological profile. Herein, we cover the goniothalamin-related styryl lactones having a C6-C3-C4 framework which appeared in the literature for the first time in the period 2000-2017, and the reports on the synthesis, biological activity and mechanism of action which were published from 2007-2017.
Goniothalamin, styryl lactones, isolation, synthesis, biological activity, mode of action.
Department of Organic Chemistry, Institute of Chemistry, University of Campinas, Campinas, Department of Organic Chemistry, Institute of Chemistry, University of Campinas, Campinas, Department of Organic Chemistry, Institute of Chemistry, University of Campinas, Campinas, Department of Organic Chemistry, Institute of Chemistry, University of Campinas, Campinas