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The Associations between Central Nervous System Diseases and Haemostatic Disorders

[ Vol. 18 , Issue. 4 ]

Author(s):

Maria Podsiedlik*, Magdalena Markowicz-Piasecka, Elżbieta Mikiciuk-Olasik and Joanna Sikora   Pages 307 - 316 ( 10 )

Abstract:


The aim of this review was to examine the relationship between the occurrence of central nervous system (CNS) diseases, the medicines used in their treatment and the blood coagulation process. The paper mainly focuses on the effects of antidepressant and antipsychotic drugs. Special attention has been paid to the influence of drugs on platelets, the vascular endothelium, plasma coagulation and fibrinolysis, regarding coagulation.

Keywords:

Coagulation, haemostasis, central nervous system diseases, antidepressant drugs, antipsychotic drugs, vascular endothelium.

Affiliation:

Department of Pharmaceutical Chemistry, Drug Analysis and Radiopharmacy, Medical University of Lodz, ul. Muszynskiego 1, 90-151 Lodz, Laboratory of Bioanalysis, Department of Pharmaceutical Chemistry, Drug Analysis and Radiopharmacy, Medical University of Lodz, ul. Muszynskiego 1, 90-151 Lodz, Department of Pharmaceutical Chemistry, Drug Analysis and Radiopharmacy, Medical University of Lodz, ul. Muszynskiego 1, 90-151 Lodz, Laboratory of Bioanalysis, Department of Pharmaceutical Chemistry, Drug Analysis and Radiopharmacy, Medical University of Lodz, ul. Muszynskiego 1, 90-151 Lodz

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